IIRC a CCR5 deletion leads to HIV resistance, but the homozygous allele also leads to immune transcription disruptions. I believe there was a Chinese geneticist that deleted CCR5 from twin embryos and got “disappeared” for it, but it remains to be seen what the consequences of that change are (I don’t remember if those embryos were implanted).

I’m of the opinion that we should approach this topic with caution until we know exactly what’s going on and the consequences of said alleles. Hypothetically speaking, imagine being born and chosen by this IQ method only to realize some horrible consequence later like asthma susceptibility in a world with decreasing air quality.

I’d be extremely pissed lmao. I could still find happiness even if I was less intelligent.

There’s another discussion about genetic homogenization that I don’t care to go into atm too.

PRS are useful but not definitive when it comes to phenotype development, as you’ve hinted at, but I take issue with using them for eugenics purposes with the main reason being we do not know the underlying causal mechanism. It is too early to use them with confidence for something like this IMO.

I work with PRS and I am not confident in using them for IVF purposes (that may change when we understand what’s actually going on the proteomics level). I would equate it to something along the line of sports betting with the consequences being eugenics in nature.

We absolutely do not - geneticist who has worked on neurodevelopment projects

We don’t even know why Turner Syndrome - a disorder of X chromosomes - often leads to neurodevelopment delays. We have hypotheses that still aren’t tested, so anyone claiming to know the genetics of neurodevelopment is grifting you.

Ain’t that just the way

It was a group of family and friends lol. I wouldn’t expect them to have a good answer for that

Visited this Cathedral when I was in Seville and was surprised to see it.

I then ruined the mood for the group by asking why one of the biggest Catholic churches in the world has one of the world’s most famous slavers buried there Lmao

You and I will agree that Israel is escalating this near century old conflict and the US needs to stop sending weapons to them, but nothing good will come from more bombs being dropped in the region.

It’s indiscriminate bombing in response to indiscriminate bombing. No one benefits from this.

I haven’t seen those videos and I’d like to see them to be informed. Pls link.

I just know that even the US struggles with targeted ballistics not hitting civilians and I think any focus on that argument weakens her response. Israel’s mandatory conscription makes those standalone sentences mean even less.

The call to action of boycotting Israel at the end is the valuable part of this quote.

I wouldn’t die on the hill of “Hezbollah is not targeting civilians or civilian infrastructure” for the fact that they do not have the rocketry capabilities for targeted strikes. Isreal clearly doesn’t either.

Coincidentally I just finished the Behind the Bastards update episode on the Bankman-Fried case from back in 2023. Apparently her diary was leaked by Sam to the press in an attempt to discredit her testimony which backfired on him lmao.

Good to see her also receive consequences.

Power projection and spite.

Iran cares to fuck with the US, Isreal, and other western powers, likely a ripple effect of this, and Isreal has demonstrated Iran cannot control its own airspace.

Palestinians have been seeking outside support since the 1948 UN resolution to create the 2 nations / the nakba, even going so far as getting support from the right wing Israeli government .

It’s a business deal not a moral one.

Israel’s actions have also put them, and the US, in a (demonstrably) bad light on the world stage, so any support to Palestinians is a PR win for Iran and everyone who’s competing with the US for influence so Russia and China love it too.

Let’s get an arena with Hamas, Hezbollah, and the Likud party members all together to fight it out to the death so the rest of us can find some real solutions. Anyone who disagrees with peace gets put into the fighting pit.

IIRC before these changes take affect, Mexico’s President appoints (at least supreme) court judges who have tenure for 15 years. The ruling party is arguing for these changes to combat corruption. Rumor is that the Mexican legal system is corrupt af, and I haven’t seen any alternatives proposed by the opposition in (English) coverage of the protests, but we’ll see how electing judges goes I guess.

The incidents on the border mission that led to troops dying have varied. Some of the soldier deaths reported include one who died from a medical emergency at a hotel where troops were staying in McAllen, and another who was accidentally shot in Fort Clark Springs. Two other soldiers died in a traffic accident in Laredo — one in the accident and the other by suicide in the minutes after the crash. At least four additional soldiers have died by suicide while assigned to the border.

• the Sergeant who drowned trying to save people in the Rio Grande

This article is a ride and it makes this national guard deployment look even worse.

Yeah, this is a manifestation of those horny thoughts that go too far unfortunately. I’m unsure how you would even tackle this problem

You clearly cannot read lmao

The point is he was punished and likely contributed to him not being barred from Olympic participation. Ignore the double jeopardy statement then, engage with the actual discussion about the non rapist.

https://www.law.cornell.edu/wex/double_jeopardy#:~:text=The Double Jeopardy Clause in,for substantially the same crime.

From the US, but the philosophical reasoning still applies.

You misunderstand the point. The Netherlands did not stop him from competing for them, presumably because he’s served his time for the crime by their standards.

That’s your problem with the Netherland’s Olympic committee then, not the other athletes - the whole point of the post.

I don’t think that guy’s really complaining about the booing, I think he’s trying to separate the rapist from the other competitors.

I don’t know the case, and I’m very surprised the Netherlands let this guy compete for them, but he is and apparently served prison time (not as much as he probably should’ve). If he’s already served a prison sentence, then the Netherlands government probably believes he has been punished for the crime and is “rehabilited”. If he’s served time, double jeopardy applies to any punishment he would receive after the fact (IIRC).

I don’t know the rapist and I don’t care about him, I’d hope he’s incredibly remorseful and I’m not defending what he did, but like the OP was driving at; why are the actions of the rapist POS who served prison time tainting the other athletes competing for their own interests / country that legally posits the guy has been punished for his actions? Imagine being proud of your work and being booed because of the previous unrelated actions of a coworker you may or may not like.

If murderers are able to serve their prison sentence and be freed after their crime and feel remorse for their actions etc., at what point in time does someone stop being punished for their previous actions? I’m bringing up the rhetorical question in response to the common vitriol in comments surrounding sex crimes that bleeds onto anyone involved.

Unless you believe in the death penalty and that the rapist deserved to die for his actions by the hands of his government, what does it take for everyone to move forward? I ask because you’re positing the other Netherland’s athlete is essentially guilty because he didn’t risk his Olympic ambitions and refuse to play with the rapist who legally served his sentence.

How long he should’ve been in prison is another debate.