Some fungal diseases in humans no longer respond to medicines, which increases the risk of severe illness and death as well disease spread, according to a new report.

On Tuesday, the World Health Organization (WHO) published what it calls its first-ever report on the lack of tests and treatments for fungal infections.

Yeasts, moulds and mushrooms are all examples of fungi. Common toenail infections or vaginal yeast infections are common and treatable, but that’s not always the case.

“Fungal diseases are an increasing public health concern, with common infections — such as Candida, which causes oral and vaginal thrush — growing increasingly resistant to treatment,” WHO said.

  • HellsBelle@sh.itjust.worksOPEnglish
    21·
    2 days ago

    Fyi for those interested …

    The fungi in the top ‘critical priority’ category of the WHO’s fungal priority pathogens list (FPPL) are deadly, with mortality rates reaching as high as 88%. Advancements in treatments mean that more people are likely to be living with immunocompromised conditions, which also could mean increases in cases of invasive fungal diseases. This is a complex challenge to manage due to inaccessibility of diagnostic tools, limited availability of antifungal medicines, and a slow and complex R&D process for new treatments.

    https://www.who.int/publications/i/item/9789240060241

    The critical group includes Cryptococcus neoformans, Candida auris, Aspergillus fumigatus and Candida albicans.

    The high group includes Nakaseomyces glabrata (Candida glabrata), Histoplasma spp., eumycetoma causative agents, Mucorales, Fusarium spp., Candida tropicalis and Candida parapsilosis.

    Finally, pathogens in the medium group are Scedosporium spp., Lomentospora prolificans, Coccidioides spp., Pichia kudriavzeveii (Candida krusei), Cryptococcus gattii, Talaromyces marneffei, Pneumocystis jirovecii and Paracoccidioides spp.

    PDF https://iris.who.int/bitstream/handle/10665/363682/9789240060241-eng.pdf?sequence=1